Telomerase reverse transcriptase in people with pituitary adenomas

Takeaway

  • Telomerase reverse transcriptase (TERT) promoter methylation and upregulated TERT expression is associated with disease progression, and short progression-free survival (PFS) in people with pituitary adenomas.

Why this matters

  • Recognising consequences of TERT abnormalities in pituitary adenomas may help inform clinical treatment decisions.