Retrospective cohort study of the development of brain metastases in patients with breast cancer


  • Patients with triple negative breast cancer (TNBC) have a higher intracranial tumor burden, which also develops at a higher rate, versus non-TNBC. Although whole brain radiation therapy (WBRT) is standard of care in patients with numerous metastases, it did not offer survival benefits in patients with TNBC.

Why this matters

  • Almost half of patients with TNBC develop brain metastases, but there are no extensive studies on the management of brain metastases in TNBC.

  • The findings from this study may influence clinical decision making, as new brain metastases may have developed from the time of initial brain imaging to radiation therapy.

International Medical Press is a global provider of independent medical education. Its mission is to provide healthcare professionals with high-quality, trusted medical information with the aim of helping optimize patient care.

No responsibility is assumed by International Medical Press for any injury and/or damage to persons or property through negligence or otherwise, or from any use or operation of any methods, products, instructions, or ideas contained in the material herein. Because of rapid advances in the medical sciences, International Medical Press recommends that independent verification of diagnoses and drug dosages should be made. The opinions expressed do not reflect those of International Medical Press or the sponsor. International Medical Press assumes no liability for any material contained herein.