Pinpointing the minimally important clinical difference for fall treatment in Parkinson’s Disease

Takeaway

  • Specialists in Parkinson’s disease (PD) came to consensus that preventing 5 falls per year (25% relative reduction of falls rate) was the minimum clinically important difference (MCID).

Why this matters

  • Identification of a MCID of falls in PD among experts helps inform the design of future clinical trials, ensuring trials are powered with adequate sample sizes to detect a clinically meaningful effect of PD therapy.