Mechanisms behind involuntary muscle activity in cerebral palsy and stroke

Takeaway

  • Individuals with cerebral palsy (CP) and stroke both experience sustained involuntary muscle activity but by different mechanisms; a larger contribution from the motor cortex was observed in those with CP while afferent neural feedback played a larger role in those with stroke.

Why this matters

    Optimal treatment of involuntary muscle activity may differ in those with CP and stroke, with a focus on plastic adaptations to central motor control in CP and addressing deficits in integration of sensory feedback in stroke.