A combination of four proteins are modulated in the 24 hours following an epileptic seizure (ES), providing a clear plasma biomarker to distinguish ES from psychogenic non-epileptic seizures (PNES).
Why this matters
Accurate diagnosis of epilepsy is challenging, and misdiagnosis is common.
PNES can mimic ES and are commonly misdiagnosed as ES.
Neuroinflammation is highly associated with ES and could act as a differential biomarker for the diagnosis of ES vs PNES.