Evidence of abnormal inhibitory plasticity in cervical dystonia

Takeaway

  • Following high frequency repetitive somatosensory stimulation (HF-RSS), individuals with cervical dystonia (CD) had a reduction in somatosensory temporal discrimination threshold (STDT) and measures of physiological neuronal inhibition, indicating abnormal inhibitory plasticity in the somatosensory cortex (S1) in CD.

Why this matters

  • The observation of dysfunction in the inhibitory circuits in S1 for individuals with CD adds to the body of evidence that CD is caused by loss of inhibition in various areas of the central nervous system.