1-year follow-up of grey matter atrophy in multiple sclerosis


  • There are differential patterns of grey matter (GM) atrophy across disease stages of multiple sclerosis (MS), which typically progressed at 1-year of follow-up. In particular, cerebellar GM atrophy predicted clinical progression.

Why this matters

  • GM is increasingly recognized as a key component in the pathophysiology of MS, and its atrophy has been associated with clinical disability.

  • Voxel-based morphometry is a conventional approach used to investigate GM atrophy, but is limited in its ability to analyze distinct patterns (or networks) of GM density that usually co-vary between different people.

International Medical Press is a global provider of independent medical education. Its mission is to provide healthcare professionals with high-quality, trusted medical information with the aim of helping optimize patient care.

No responsibility is assumed by International Medical Press for any injury and/or damage to persons or property through negligence or otherwise, or from any use or operation of any methods, products, instructions, or ideas contained in the material herein. Because of rapid advances in the medical sciences, International Medical Press recommends that independent verification of diagnoses and drug dosages should be made. The opinions expressed do not reflect those of International Medical Press or the sponsor. International Medical Press assumes no liability for any material contained herein.